Disruption of K(ATP) Channel Expression in Skeletal Muscle by Targeted Oligonucleotide Delivery Promotes Activity-linked Thermogenesis

Despite the medical, social, and economic impact of obesity, only a few therapeutic options, focused largely on reducing caloric intake, are currently available and these have limited success rates. A major impediment is that any challenge by caloric restriction is counterbalanced by activation of s...

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Vydáno v:Mol Ther
Hlavní autoři: Koganti, Siva Rama Krishna, Zhu, Zhiyong, Subbotina, Ekaterina, Gao, Zhan, Sierra, Ana, Proenza, Manuel, Yang, Liping, Alekseev, Alexey, Hodgson-Zingman, Denice, Zingman, Leonid
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395784/
https://ncbi.nlm.nih.gov/pubmed/25648265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.21
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