Gambogic Acid Disrupts Toll-like Receptor4 Activation by Blocking Lipopolysaccharides Binding to Myeloid Differentiation Factor 2

Our body’s immune system has defense mechanisms against pathogens such as viruses and bacteria. Immune responses are primarily initiated by the activation of toll-like receptors (TLRs). In particular, TLR4 is well-characterized and is known to be activated by gram-negative bacteria and tissue damage...

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Veröffentlicht in:Toxicol Res
Hauptverfasser: Lee, Jin Young, Lee, Byung Ho, Lee, Joo Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society Of Toxicology 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395650/
https://ncbi.nlm.nih.gov/pubmed/25874028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2015.31.1.011
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