WIN 55,212-2, Agonist of Cannabinoid Receptors, Prevents Amyloid β(1-42) Effects on Astrocytes in Primary Culture

Alzheimer´s disease (AD), a neurodegenerative illness involving synaptic dysfunction with extracellular accumulation of Aβ(1-42) toxic peptide, glial activation, inflammatory response and oxidative stress, can lead to neuronal death. Endogenous cannabinoid system is implicated in physiological and p...

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Publicado en:PLoS One
Main Authors: Aguirre-Rueda, Diana, Guerra-Ojeda, Sol, Aldasoro, Martin, Iradi, Antonio, Obrador, Elena, Mauricio, Maria D., Vila, Jose Mª, Marchio, Patricia, Valles, Soraya L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395436/
https://ncbi.nlm.nih.gov/pubmed/25874692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122843
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