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Genetic Analysis of Ligation-Induced Neointima Formation in an F2 Intercross of C57BL/6 and FVB/N Inbred Mouse Strains

OBJECTIVE: Proliferation and migration of vascular smooth muscle cells (SMCs) are central for arterial diseases including atherosclerosis and restenosis. We hypothesized that the underlying mechanisms may be modeled by carotid ligation in mice. In FVB/N inbred mice, ligation leads to abundant neoint...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Östergren, Caroline, Shim, Jeong, Larsen, Jens Vinther, Nielsen, Lars Bo, Bentzon, Jacob F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395357/
https://ncbi.nlm.nih.gov/pubmed/25875831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121899
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