Murine CMV-Induced Hearing Loss Is Associated with Inner Ear Inflammation and Loss of Spiral Ganglia Neurons

Congenital human cytomegalovirus (HCMV) occurs in 0.5–1% of live births and approximately 10% of infected infants develop hearing loss. The mechanism(s) of hearing loss remain unknown. We developed a murine model of CMV induced hearing loss in which murine cytomegalovirus (MCMV) infection of newborn...

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Publicado en:PLoS Pathog
Autores principales: Bradford, Russell D., Yoo, Young-Gun, Golemac, Mijo, Pugel, Ester Pernjak, Jonjic, Stipan, Britt, William J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395355/
https://ncbi.nlm.nih.gov/pubmed/25875183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004774
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