Immune Tolerance Induction Using Fetal Directed Placental Injection in Rodent Models: A Murine Model

OBJECTIVES: Induction of the immune response is a major problem in replacement therapies for inherited protein deficiencies. Tolerance created in utero can facilitate postnatal treatment. In this study, we aimed to induce immune tolerance towards a foreign protein with early gestational cell transpl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Takahashi, Kei, Endo, Masayuki, Miyoshi, Takekazu, Tsuritani, Mitsuhiro, Shimazu, Yukiko, Hosoda, Hiroshi, Saga, Kotaro, Tamai, Katsuto, Flake, Alan W., Yoshimatsu, Jun, Kimura, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395343/
https://ncbi.nlm.nih.gov/pubmed/25876079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123712
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