Parasite Load Induces Progressive Spleen Architecture Breakage and Impairs Cytokine mRNA Expression in Leishmania infantum-Naturally Infected Dogs

Canine Visceral Leishmaniasis (CVL) shares many aspects with the human disease and dogs are considered the main urban reservoir of L. infantum in zoonotic VL. Infected dogs develop progressive disease with a large clinical spectrum. A complex balance between the parasite and the genetic/immunologica...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Cavalcanti, Amanda S., Ribeiro-Alves, Marcelo, Pereira, Luiza de O. R., Mestre, Gustavo Leandro, Ferreira, Anna Beatriz Robottom, Morgado, Fernanda N., Boité, Mariana C., Cupolillo, Elisa, Moraes, Milton O., Porrozzi, Renato
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395300/
https://ncbi.nlm.nih.gov/pubmed/25875101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123009
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