Age-Related Nuclear Translocation of P2X6 Subunit Modifies Splicing Activity Interacting with Splicing Factor 3A1

P2X receptors are ligand-gated ion channels sensitive to extracellular nucleotides formed by the assembling of three equal or different P2X subunits. In this work we report, for the first time, the accumulation of the P2X6 subunit inside the nucleus of hippocampal neurons in an age-dependent way. Th...

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Bibliographic Details
Published in:PLoS One
Main Authors: Díaz-Hernández, Juan Ignacio, Sebastián-Serrano, Álvaro, Gómez-Villafuertes, Rosa, Díaz-Hernández, Miguel, Miras-Portugal, María Teresa
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395284/
https://ncbi.nlm.nih.gov/pubmed/25874565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123121
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