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Knockdown of the Cell Cycle Inhibitor p21 Enhances Cartilage Formation by Induced Pluripotent Stem Cells

The limited regenerative capacity of articular cartilage contributes to progressive joint dysfunction associated with cartilage injury or osteoarthritis. Cartilage tissue engineering seeks to provide a biological substitute for repairing damaged or diseased cartilage, but requires a cell source with...

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Bibliographic Details
Published in:Tissue Eng Part A
Main Authors: Diekman, Brian O., Thakore, Pratiksha I., O'Connor, Shannon K., Willard, Vincent P., Brunger, Jonathan M., Christoforou, Nicolas, Leong, Kam W., Gersbach, Charles A., Guilak, Farshid
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394871/
https://ncbi.nlm.nih.gov/pubmed/25517798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2014.0240
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