Discovery of Itraconazole with Broad-Spectrum In Vitro Antienterovirus Activity That Targets Nonstructural Protein 3A

There is currently no approved antiviral therapy for the prophylaxis or treatment of enterovirus infections, which remain a substantial threat to public health. To discover inhibitors that can be immediately repurposed for treatment of enterovirus infections, we developed a high-throughput screening...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Gao, Qianqian, Yuan, Shilin, Zhang, Chao, Wang, Ying, Wang, Yizhuo, He, Guimei, Zhang, Shuyi, Altmeyer, Ralf, Zou, Gang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394834/
https://ncbi.nlm.nih.gov/pubmed/25691649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05108-14
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