Potential of Novel Antimicrobial Peptide P3 from Bovine Erythrocytes and Its Analogs To Disrupt Bacterial Membranes In Vitro and Display Activity against Drug-Resistant Bacteria in a Mouse Model

With the emergence of many antibiotic-resistant strains worldwide, antimicrobial peptides (AMPs) are being evaluated as promising alternatives to conventional antibiotics. P3, a novel hemoglobin peptide derived from bovine erythrocytes, exhibited modest antimicrobial activity in vitro. We evaluated...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zhang, Qinghua, Xu, Yanzhao, Wang, Qing, Hang, Bolin, Sun, Yawei, Wei, Xiaoxiao, Hu, Jianhe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394822/
https://ncbi.nlm.nih.gov/pubmed/25753638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04932-14
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