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Bestatin Induces Specific Changes in Trypanosoma cruzi Dipeptide Pool

Proteases and peptidases in Trypanosoma cruzi are considered potential targets for antichagasic chemotherapy. We monitored changes in low-mass metabolites in T. cruzi epimastigotes treated with bestatin, a dipeptide metalloaminopeptidase inhibitor. After treatment, multiple dipeptides were shown to...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Trochine, Andrea, Creek, Darren J., Faral-Tello, Paula, Barrett, Michael P., Robello, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394807/
https://ncbi.nlm.nih.gov/pubmed/25712359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05046-14
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