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Discovery of Benzo[f]indole-4,9-dione Derivatives as New Types of Anti-Inflammatory Agents

Certain benzo[f]indole-4,9-dione derivatives were synthesized and evaluated for their inhibitory effects on superoxide anion generation and neutrophil elastase (NE) release in formyl-l-methionyl-l-leucyl-l-phenylalanine (fMLF)-activated human neutrophils. Results indicated that (Z)-1-benzyl-4-(hydro...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, You-Ren, Tseng, Chih-Hua, Chen, Yeh-Long, Hwang, Tsong-Long, Tzeng, Cherng-Chyi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394546/
https://ncbi.nlm.nih.gov/pubmed/25807261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16036532
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