Ameliorative Effects of PACAP against Cartilage Degeneration. Morphological, Immunohistochemical and Biochemical Evidence from in Vivo and in Vitro Models of Rat Osteoarthritis

Osteoarthritis (OA); the most common form of degenerative joint disease, is associated with variations in pro-inflammatory growth factor levels, inflammation and hypocellularity resulting from chondrocyte apoptosis. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide endowed...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Giunta, Salvatore, Castorina, Alessandro, Marzagalli, Rubina, Szychlinska, Marta Anna, Pichler, Karin, Mobasheri, Ali, Musumeci, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394513/
https://ncbi.nlm.nih.gov/pubmed/25782157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16035922
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