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Rational Design of a Novel AMPA Receptor Modulator through a Hybridization Approach
[Image: see text] The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are a family of glutamate ion channels of considerable interest in excitatory neurotransmission and associated disease processes. Here, we demonstrate how exploitation of the available X-ray crystal structure...
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| Publicado no: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394345/ https://ncbi.nlm.nih.gov/pubmed/25893038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5004553 |
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