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F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging

[Image: see text] A series of fluorine-substituted monomeric and dimeric cRGD peptide derivatives, such as cRGD-ADIBOT-F (ADIBOT = azadibenzocyclooctatriazole), di-cRGD-ADIBOT-F, cRGD-PEG(5)-ADIBOT-F, and di-cRGD-PEG(5)-ADIBOT-F, were prepared by strain-promoted alkyne azide cycloaddition (SPAAC) re...

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Detalles Bibliográficos
Publicado en:ACS Med Chem Lett
Autores principales: Kim, Hye Lan, Sachin, Kalme, Jeong, Hyeon Jin, Choi, Wonsil, Lee, Hyun Soo, Kim, Dong Wook
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2015
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394342/
https://ncbi.nlm.nih.gov/pubmed/25893040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500464f
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