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RNA transcribed from a distal enhancer is required for activating the chromatin at the promoter of the gonadotropin α-subunit gene

Since the discovery that many transcriptional enhancers are transcribed into long noncoding RNAs termed “enhancer RNAs” (eRNAs), their putative role in enhancer function has been debated. Very recent evidence has indicted that some eRNAs play a role in initiating or activating transcription, possibl...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pnueli, Lilach, Rudnizky, Sergei, Yosefzon, Yahav, Melamed, Philippa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394321/
https://ncbi.nlm.nih.gov/pubmed/25810254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414841112
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