Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis

Mycobacterium lepromatosis is an uncultured human pathogen associated with diffuse lepromatous leprosy and a reactional state known as Lucio's phenomenon. By using deep sequencing with and without DNA enrichment, we obtained the near-complete genome sequence of M. lepromatosis present in a skin...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Singh, Pushpendra, Benjak, Andrej, Schuenemann, Verena J., Herbig, Alexander, Avanzi, Charlotte, Busso, Philippe, Nieselt, Kay, Krause, Johannes, Vera-Cabrera, Lucio, Cole, Stewart T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394283/
https://ncbi.nlm.nih.gov/pubmed/25831531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421504112
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