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Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis
Infections caused by antibiotic-resistant bacteria are a rising public health threat and make the identification of new antibiotics a priority. From a cell-based screen for bactericidal compounds against Mycobacterium tuberculosis under nutrient-deprivation conditions we identified auranofin, an ora...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394260/ https://ncbi.nlm.nih.gov/pubmed/25831516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504022112 |
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