The effect of sulforaphane on histone deacetylase activity in keratinocytes: differences between in vitro and in vivo analyses

Sulforaphane is a natural product found in broccoli which is known to exert many different molecular effects in the cell, including inhibition of histone deacetylase (HDAC) enzymes. Here we examine for the first time the potential for sulforaphane to inhibit HDACs in HaCaT keratinocytes and compare...

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Publicat a:Mol Carcinog
Autors principals: Dickinson, Sally E., Rusche, Jadrian J., Bec, Sergiu L., Horn, David J., Janda, Jaroslav, Rim, So Hyun, Smith, Catharine L., Bowden, G. Timothy
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394046/
https://ncbi.nlm.nih.gov/pubmed/25307283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22224
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