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The effect of sulforaphane on histone deacetylase activity in keratinocytes: differences between in vitro and in vivo analyses

Sulforaphane is a natural product found in broccoli which is known to exert many different molecular effects in the cell, including inhibition of histone deacetylase (HDAC) enzymes. Here we examine for the first time the potential for sulforaphane to inhibit HDACs in HaCaT keratinocytes and compare...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Dickinson, Sally E., Rusche, Jadrian J., Bec, Sergiu L., Horn, David J., Janda, Jaroslav, Rim, So Hyun, Smith, Catharine L., Bowden, G. Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394046/
https://ncbi.nlm.nih.gov/pubmed/25307283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22224
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