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Genome-engineering with CRISPR-Cas9 in the mosquito Aedes aegypti

The mosquito Aedes aegypti is a potent vector of the chikungunya, yellow fever, and dengue viruses, responsible for hundreds of millions of infections and over 50,000 human deaths per year. Mutagenesis in Ae. aegypti has been established with TALENs, ZFNs, and homing endonucleases, which require the...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Kistler, Kathryn E, Vosshall, Leslie B, Matthews, Benjamin J
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394034/
https://ncbi.nlm.nih.gov/pubmed/25818303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.009
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