TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by widespread epidemiological and molecular heterogeneity. Previous work showed that in the western part of North Africa, a region of low incidence of HCC, mutations are scarce for this tumor type. As epigenetic changes are considered possi...

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Publicat a:Mol Cancer
Autors principals: Rebbani, Khadija, Marchio, Agnès, Ezzikouri, Sayeh, Afifi, Rajaa, Kandil, Mostafa, Bahri, Olfa, Triki, Henda, Essaid El Feydi, Abdellah, Dejean, Anne, Benjelloun, Soumaya, Pineau, Pascal
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393630/
https://ncbi.nlm.nih.gov/pubmed/25889455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0340-2
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