Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat

BACKGROUND: The current epidemic of obesity and associated diseases calls for swift actions to better understand the mechanisms by which genetics and environmental factors affect metabolic health in humans. Monozygotic (MZ) twin pairs showing discordance for obesity suggest that epigenetic influence...

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Bibliografske podrobnosti
izdano v:Clin Epigenetics
Main Authors: Ollikainen, Miina, Ismail, Khadeeja, Gervin, Kristina, Kyllönen, Anjuska, Hakkarainen, Antti, Lundbom, Jesper, Järvinen, Elina A, Harris, Jennifer R, Lundbom, Nina, Rissanen, Aila, Lyle, Robert, Pietiläinen, Kirsi H, Kaprio, Jaakko
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393626/
https://ncbi.nlm.nih.gov/pubmed/25866590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0073-5
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