Mesenchymal stem cell-derived microparticles ameliorate peritubular capillary rarefaction via inhibition of endothelial-mesenchymal transition and decrease tubulointerstitial fibrosis in unilateral ureteral obstruction

INTRODUCTION: Microparticles (MPs) derived from kidney-derived mesenchymal stem cells (KMSCs) have recently been reported to ameliorate rarefaction of peritubular capillaries (PTC) in ischemic kidneys via delivery of proangiogenic effectors. This study aimed to investigate whether KMSC-derived MPs s...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Choi, Hoon Young, Lee, Hyun Gyu, Kim, Beom Seok, Ahn, Sun Hee, Jung, Ara, Lee, Mirae, Lee, Jung Eun, Kim, Hyung Jong, Ha, Sung Kyu, Park, Hyeong Cheon
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393614/
https://ncbi.nlm.nih.gov/pubmed/25889661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0012-6
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