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Early goal-directed therapy in the management of severe sepsis or septic shock in adults: a meta-analysis of randomized controlled trials

BACKGROUND: The Surviving Sepsis Campaign guidelines have proposed early goal-directed therapy (EGDT) as a key strategy to decrease mortality among patients with severe sepsis or septic shock. However, its effectiveness is uncertain. METHODS: We searched for relevant studies in Medline, Embase, the...

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Pubblicato in:BMC Med
Autori principali: Zhang, Ling, Zhu, Guijun, Han, Li, Fu, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393610/
https://ncbi.nlm.nih.gov/pubmed/25885654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0312-9
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