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Population-based structural variation discovery with Hydra-Multi

Summary: Current strategies for SNP and INDEL discovery incorporate sequence alignments from multiple individuals to maximize sensitivity and specificity. It is widely accepted that this approach also improves structural variant (SV) detection. However, multisample SV analysis has been stymied by th...

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Foilsithe in:Bioinformatics
Main Authors: Lindberg, Michael R., Hall, Ira M., Quinlan, Aaron R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393510/
https://ncbi.nlm.nih.gov/pubmed/25527832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu771
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