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The GTPase-Activating Protein Rga1 Interacts with Rho3 GTPase and May Regulate Its Function in Polarized Growth in Budding Yeast

In budding yeast, Rga1 negatively regulates the Rho GTPase Cdc42 by acting as a GTPase-activating protein (GAP) for Cdc42. To gain insight into the function and regulation of Rga1, we overexpressed Rga1 and an N-terminally truncated Rga1-C538 (a.a. 538-1007) segment. Overexpression of Rga1-C538 but...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: He, Fei, Nie, Wen-Chao, Tong, Zongtian, Yuan, Si-Min, Gong, Ting, Liao, Yuan, Bi, Erfei, Gao, Xiang-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393305/
https://ncbi.nlm.nih.gov/pubmed/25860339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123326
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