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Tracheal Dysplasia Precedes Bronchial Dysplasia in Mouse Model of N-Nitroso Trischloroethylurea Induced Squamous Cell Lung Cancer

Squamous cell lung cancer (SCC) is the second leading cause of lung cancer death in the US and has a 5-year survival rate of only 16%. Histological changes in the bronchial epithelium termed dysplasia are precursors to invasive SCC. However, the cellular mechanisms that cause dysplasia are unknown....

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Ghosh, Moumita, Dwyer-Nield, Lori D., Kwon, Jennifer B., Barthel, Lea, Janssen, William J., Merrick, Daniel T., Keith, Robert L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393296/
https://ncbi.nlm.nih.gov/pubmed/25860262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122823
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