Full-Length Human Placental sFlt-1-e15a Isoform Induces Distinct Maternal Phenotypes of Preeclampsia in Mice

OBJECTIVE: Most anti-angiogenic preeclampsia models in rodents utilized the overexpression of a truncated soluble fms-like tyrosine kinase-1 (sFlt-1) not expressed in any species. Other limitations of mouse preeclampsia models included stressful blood pressure measurements and the lack of postpartum...

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Udgivet i:PLoS One
Main Authors: Szalai, Gabor, Romero, Roberto, Chaiworapongsa, Tinnakorn, Xu, Yi, Wang, Bing, Ahn, Hyunyoung, Xu, Zhonghui, Chiang, Po Jen, Sundell, Birgitta, Wang, Rona, Jiang, Yang, Plazyo, Olesya, Olive, Mary, Tarca, Adi L., Dong, Zhong, Qureshi, Faisal, Papp, Zoltan, Hassan, Sonia S., Hernandez-Andrade, Edgar, Than, Nandor Gabor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393117/
https://ncbi.nlm.nih.gov/pubmed/25860260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119547
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