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Comparison of a Novel Oxysterol Molecule and rhBMP2 Fusion Rates in a Rabbit Posterolateral Lumbar Spine Model

BACKGROUND CONTEXT: The non-union rate following lumbar spinal fusion is as high as 25%. Bone morphogenetic protein-2 (rhBMP2) has been used as a biological adjunct to promote bony fusion. However, recently there have been concerns about BMP2. Oxysterol 133 (Oxy133) has been shown to promote excelle...

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Bibliographische Detailangaben
Veröffentlicht in:Spine J
Hauptverfasser: Scott, Trevor P., Phan, Kevin H., Tian, Haijun, Suzuki, Akinobu, Montgomery, Scott R., Johnson, Jared S., Atti, Elisa, Tetratis, Sotirios, Pereira, Renata C., Wang, Jeffrey C., Daubs, Michael D., Stappenbeck, Frank, Parhami, Farhad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392926/
https://ncbi.nlm.nih.gov/pubmed/25450659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2014.11.014
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