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Involvement of Reactive Oxygen Species in Apoptosis Induced by Pharmacological Inhibition of Protein Kinase CK2
It has been reported that inhibition of protein kinase CK2 (CK2) with antisense oligodeoxynucleotides (ODN) is a potent inducer of apoptosis in cancer cells but not in normal cells. In this regard, the apoptotic-inducing effect is attributed to the catalytic activity of the enzyme, which phosphoryla...
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| Опубликовано в: : | Ann N Y Acad Sci |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392777/ https://ncbi.nlm.nih.gov/pubmed/19723109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.04916.x |
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