Cholesterol removal from adult skeletal muscle impairs excitation–contraction coupling and aging reduces caveolin-3 and alters the expression of other triadic proteins

Cholesterol and caveolin are integral membrane components that modulate the function/location of many cellular proteins. Skeletal muscle fibers, which have unusually high cholesterol levels in transverse tubules, express the caveolin-3 isoform but its association with transverse tubules remains cont...

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Vydáno v:Front Physiol
Hlavní autoři: Barrientos, Genaro, Llanos, Paola, Hidalgo, Jorge, Bolaños, Pura, Caputo, Carlo, Riquelme, Alexander, Sánchez, Gina, Quest, Andrew F. G., Hidalgo, Cecilia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392612/
https://ncbi.nlm.nih.gov/pubmed/25914646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00105
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