Loading...
PU.1 downregulation in murine radiation-induced acute myeloid leukaemia (AML): from molecular mechanism to human AML
The transcription factor PU.1, encoded by the murine Sfpi1 gene (SPI1 in humans), is a member of the Ets transcription factor family and plays a vital role in commitment and maturation of the myeloid and lymphoid lineages. Murine studies directly link primary acute myeloid leukaemia (AML) and decrea...
Saved in:
| Published in: | Carcinogenesis |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2015
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392607/ https://ncbi.nlm.nih.gov/pubmed/25750172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv016 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|