The role of histologic subtype, p16(INK4a) expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

BACKGROUND: Up to 50% of penile squamous cell carcinomas (pSCC) develop in the context of high-risk human papillomavirus (HR-HPV) infection. Most of these tumours have been reported to show basaloid differentiation and overexpression of tumour suppressor protein p16(INK4a). Whether HPV-triggered car...

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Pubblicato in:BMC Cancer
Autori principali: Steinestel, Julie, Al Ghazal, Andreas, Arndt, Annette, Schnoeller, Thomas J, Schrader, Andres J, Moeller, Peter, Steinestel, Konrad
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392470/
https://ncbi.nlm.nih.gov/pubmed/25885064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1268-z
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