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LKB1 Knockout Mouse Develops Spontaneous Atrial Fibrillation and Provides Mechanistic Insights Into Human Disease Process

BACKGROUND: Atrial fibrillation (AF) is a complex disease process, and the molecular mechanisms underlying initiation and progression of the disease are unclear. Consequently, AF has been difficult to model. In this study, we have presented a novel transgenic mouse model of AF that mimics human dise...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Ozcan, Cevher, Battaglia, Emily, Young, Rebeccah, Suzuki, Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392447/
https://ncbi.nlm.nih.gov/pubmed/25773299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001733
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