Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation

BACKGROUND: Genome-wide association studies (GWAS) have shown that the common single nucleotide polymorphism (SNP) rs6800541 located in SCN10A, encoding the voltage-gated Na(v)1.8 sodium channel, is associated with PR–interval prolongation and atrial fibrillation (AF). SNP rs6800541 is in high linka...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Circ Cardiovasc Genet
Hauptverfasser: Jabbari, Javad, Olesen, Morten S., Yuan, Lei, Nielsen, Jonas B., Liang, Bo, Macri, Vincenzo, Christophersen, Ingrid E., Nielsen, Nikolaj, Sajadieh, Ahmad, Ellinor, Patrick T., Grunnet, Morten, Haunsø, Stig, Holst, Anders G., Svendsen, Jesper H., Jespersen, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392342/
https://ncbi.nlm.nih.gov/pubmed/25691686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HCG.0000000000000022
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge