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An algorithm to generate low-resolution protein tertiary structures from knowledge of secondary structure.

An algorithm is described to assemble the three-dimensional fold of a protein starting from its secondary structure. A reduced representation of the polypeptide chain is used together with a crude potential based on pair hydrophobicities. The method is shown to be successful in locating the native t...

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Bibliografiske detaljer
Main Authors: Monge, A, Friesner, R A, Honig, B
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43923/
https://ncbi.nlm.nih.gov/pubmed/8197177
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