Structure of a BAG6 (Bcl-2-associated Athanogene 6)-Ubl4a (Ubiquitin-like Protein 4a) Complex Reveals a Novel Binding Interface That Functions in Tail-anchored Protein Biogenesis

BAG6 is an essential protein that functions in two distinct biological pathways, ubiquitin-mediated protein degradation of defective polypeptides and tail-anchored (TA) transmembrane protein biogenesis in mammals, although its structural and functional properties remain unknown. We solved a crystal...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Kuwabara, Naoyuki, Minami, Ryosuke, Yokota, Naoto, Matsumoto, Hirofumi, Senda, Toshiya, Kawahara, Hiroyuki, Kato, Ryuichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392246/
https://ncbi.nlm.nih.gov/pubmed/25713138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631804
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