Progressive genomic convergence of two Helicobacter pylori strains during mixed infection of a patient with chronic gastritis

OBJECTIVE: To study the detailed nature of genomic microevolution during mixed infection with multiple Helicobacter pylori strains in an individual. DESIGN: We sampled 18 isolates from a single biopsy from a patient with chronic gastritis and nephritis. Whole-genome sequencing was applied to these i...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Cao, Qizhi, Didelot, Xavier, Wu, Zhongbiao, Li, Zongwei, He, Lihua, Li, Yunsheng, Ni, Ming, You, Yuanhai, Lin, Xi, Li, Zhen, Gong, Yanan, Zheng, Minqiao, Zhang, Minli, Liu, Jie, Wang, Weijun, Bo, Xiaochen, Falush, Daniel, Wang, Shengqi, Zhang, Jianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Helicobacter Pylori
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392222/
https://ncbi.nlm.nih.gov/pubmed/25007814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307345
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