Multiplex Ligation-dependent Probe Amplification Can Clarify HER2 Status in Gastric Cancers with “Polysomy 17”

Therapy with trastuzumab confers a survival benefit in HER2 positive advanced gastric and gastroesophageal adenocarcinoma. HER2 status is evaluated by immunohistochemistry (IHC) and in situ hybridization (ISH). An ISH ratio of HER2 to centromere 17 (CEP17) ≥2.0 is considered amplified. This assumes...

Full description

Saved in:
Bibliographic Details
Published in:J Cancer
Main Authors: Wang, Tao, Amemiya, Yutaka, Henry, Pauline, Seth, Arun, Hanna, Wedad, Hsieh, Eugene T.
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2015
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392047/
https://ncbi.nlm.nih.gov/pubmed/25874002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.11424
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items