Alternative CD44 splicing identifies epithelial prostate cancer cells from the mesenchymal counterparts

An epithelial to mesenchymal transition (EMT) has been shown to be a necessary precursor to prostate cancer metastasis. Additionally, the differential expression and splicing of mRNAs has been identified as a key means to distinguish epithelial from mesenchymal cells by qPCR, western blotting and im...

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Udgivet i:Med Oncol
Main Authors: Hernandez, James R., Kim, John J., Verdone, James E., Liu, Xin, Torga, Gonzalo, Pienta, Kenneth J., Mooney, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391735/
https://ncbi.nlm.nih.gov/pubmed/25850653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-015-0593-z
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