MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses

Multivalent molecules with repetitive structures including bacterial capsular polysaccharides and viral capsids elicit antibody responses through B cell receptor (BCR) crosslinking in the absence of T cell help. We report that immunization with these T cell-independent type 2 (TI-2) antigens causes...

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Publicado no:Science
Main Authors: Zeng, Ming, Hu, Zeping, Shi, Xiaolei, Li, Xiaohong, Zhan, Xiaoming, Li, Xiao-Dong, Wang, Jianhui, Choi, Jin Huk, Wang, Kuan-wen, Purrington, Tiana, Tang, Miao, Fina, Maggy, DeBerardinis, Ralph J., Moresco, Eva Marie Y., Pedersen, Gabriel, McInerney, Gerald M., Karlsson Hedestam, Gunilla B., Chen, Zhijian J., Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391621/
https://ncbi.nlm.nih.gov/pubmed/25525240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.346.6216.1486
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