Gamma-Irradiated Bacille Calmette-Guérin Vaccination Does Not Modulate the Innate Immune Response during Experimental Human Endotoxemia in Adult Males

Bacille Calmette-Guérin (BCG) vaccine exerts nonspecific immunostimulatory effects and may therefore represent a novel therapeutic option to treat sepsis-induced immunoparalysis. We investigated whether BCG vaccination modulates the systemic innate immune response in humans in vivo during experiment...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol Res
Hauptverfasser: Hamers, Linda A. C., Kox, Matthijs, Arts, Rob J. W., Blok, Bastiaan, Leentjens, Jenneke, Netea, Mihai G., Pickkers, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391613/
https://ncbi.nlm.nih.gov/pubmed/25883989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/261864
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