Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan

Using a rat model, we investigated factors contributing to the pathogenesis of irinotecan-associated fatty liver disease. Male Sprague-Dawley rats were administered 200 mg/kg irinotecan by intraperitoneal injection on days 1–4, but not on days 5–7. This schedule was repeated 3 times. Rats were sacri...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncol Rep
Auteurs principaux: SAWANO, TAKEYUKI, SHIMIZU, TAKESHI, YAMADA, TOSHIYUKI, NANASHIMA, NAOKI, MIURA, TAKUYA, MOROHASHI, SATOKO, KUDO, DAISUKE, HUI, FENG MAO, KIJIMA, HIROSHI, HAKAMADA, KENICHI, TSUCHIDA, SHIGEKI
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391592/
https://ncbi.nlm.nih.gov/pubmed/25708528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.3814
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