Association of Alzheimer disease GWAS loci with MRI-markers of brain aging

Whether novel risk variants of Alzheimer’s disease (AD) identified through genome-wide association studies (GWAS) also influence MRI-based intermediate phenotypes of AD in the general population is unclear. We studied association of 24 AD risk loci with intracranial volume (ICV), total brain volume...

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Publicado no:Neurobiol Aging
Main Authors: Chauhan, Ganesh, Adams, Hieab H.H., Bis, Joshua C, Weinstein, Galit, Yu, Lei, Töglhofer, Anna Maria, Smith, Albert Vernon, van der Lee, Sven, Gottesman, Rebecca F, Thomson, Russell, Wang, Jing, Yang, Qiong, Niessen, Wiro J., Lopez, Oscar L, Becker, James T, Phan, Thanh G, Beare, Richard J, Arfanakis, Konstantinos, Fleischman, Debra, Vernooij, Meike W., Mazoyer, Bernard, Schmidt, Helena, Srikanth, Velandai, Knopman, Dave S, Jack, Clifford R, Amouyel, Philippe, Hofman, Albert, DeCarli, Charlie, Tzourio, Christophe, van Duijn, Cornelia M, Bennett, David A, Schmidt, Reinhold, Longstreth, William T, Mosley, Thomas H, Fornage, Myriam, Launer, Lenore J, Seshadri, Sudha, Ikram, M Arfan, Debette, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391343/
https://ncbi.nlm.nih.gov/pubmed/25670335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.12.028
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