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Limited Effects of an eIF2α (S51A) Allele on Neurological Impairments in the 5xFAD Mouse Model of Alzheimer's Disease
Alzheimer's disease (AD) has been associated with increased phosphorylation of the translation initiation factor 2α (eIF2α) at serine 51. Increased phosphorylation of eIF2α alters translational control and may thereby have adverse effects on synaptic plasticity, learning, and memory. To analyze...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neural Plast |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Hindawi Publishing Corporation
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391319/ https://ncbi.nlm.nih.gov/pubmed/25883808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/825157 |
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