IRS-1 gene polymorphism and DNA damage in pregnant women with diabetes or mild gestational hyperglycemia

BACKGROUND: Pregnant women with mild gestational hyperglycemia present a high risk for hypertension and obesity, and appear to reproduce the model of metabolic syndrome in pregnancy, including hyperinsulinemia and insulin resistance. Diabetic patients have a higher frequency of the IRS-1 Gly972Arg v...

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Détails bibliographiques
Publié dans:Diabetol Metab Syndr
Auteurs principaux: Gelaleti, Rafael B, Damasceno, Débora C, Salvadori, Daisy M F, Marcondes, João Paulo C, Lima, Paula H O, Morceli, Glilciane, Calderon, Iracema M P, Rudge, Marilza V C
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391297/
https://ncbi.nlm.nih.gov/pubmed/25859280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-015-0026-3
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