Lgr5+ Cells Regenerate Hair Cells via Proliferation and Direct Transdifferentiation in Damaged Neonatal Mouse Utricle

Recruitment of endogenous progenitors is critical during tissue repair. The inner ear utricle requires mechanosensory hair cells (HCs) to detect linear acceleration. After damage, non-mammalian utricles regenerate HCs via both proliferation and direct transdifferentiation. In adult mammals, limited...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Wang, Tian, Chai, Renjie, Kim, Grace S., Pham, Nicole, Jansson, Lina, Nguyen, Duc-Huy, Kuo, Bryan, May, Lindsey, Zuo, Jian, Cunningham, Lisa L., Cheng, Alan G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391285/
https://ncbi.nlm.nih.gov/pubmed/25849379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7613
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