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Leucine alters hepatic glucose/lipid homeostasis via the myostatin-AMP-activated protein kinase pathway - potential implications for nonalcoholic fatty liver disease
BACKGROUND: Elevated plasma levels of the branched-chain amino acid (BCAA) leucine are associated with obesity and insulin resistance (IR), and thus the propensity for type 2 diabetes mellitus development. However, other clinical studies suggest the contradictory view that leucine may in fact offer...
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Vydáno v: | Clin Epigenetics |
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Hlavní autoři: | , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
BioMed Central
2014
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391119/ https://ncbi.nlm.nih.gov/pubmed/25859286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-27 |
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