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Enhanced Epithelial-to-Mesenchymal Transition Associated with Lysosome Dysfunction in Podocytes: Role of p62/Sequestosome 1 as a Signaling Hub

BACKGROUND: Autophagy is of importance in the regulation of cell differentiation and senescence in podocytes. It is possible that derangement of autophagy under different pathological conditions activates or enhances Epithelial-to-Mesenchymal Transition (EMT) in podocytes, resulting in glomerular sc...

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Detalhes bibliográficos
Publicado no:Cell Physiol Biochem
Main Authors: Li, Guangbi, Li, Cai-Xia, Xia, Min, Ritter, Joseph K., Gehr, Todd W. B., Boini, Krishna, Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391077/
https://ncbi.nlm.nih.gov/pubmed/25832774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000373989
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